Abstract
Acute Zika virus (ZIKV) infection has not been confirmed in Kenya. In 2018, we used specimens collected in a 2013 dengue serosurvey study in Mombasa to test for ZIKV IgM. We confirmed specific ZIKV IgM positivity in 5 persons. These results suggest recent ZIKV transmission in the coastal region of Kenya.
Highlights
Acute Zika virus (ZIKV) infection has not been confirmed in Kenya
Specimens were tested for dengue virus (DENV) by real-time reverse transcription PCR and DENV IgM ELISA (InBios International, Inc., https:// inbios.com)
We confirmed all positive specimens with 90% plaque reduction neutralization test (PRNT90) against ZIKV strain MR766 (African lineage) and DENV (ChimeraVax; Sanofi Pasteur, https://www. sanofi.com) [9]
Summary
Acute Zika virus (ZIKV) infection has not been confirmed in Kenya. In 2018, we used specimens collected in a 2013 dengue serosurvey study in Mombasa to test for ZIKV IgM. To understand prior transmission of ZIKV in Kenya, in 2018, we used specimens collected in 2013 for a dengue serosurvey from Mombasa amidst a dengue outbreak. Specimens were tested for dengue virus (DENV) by real-time reverse transcription PCR (rRT-PCR) and DENV IgM ELISA (InBios International, Inc., https:// inbios.com).
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