Zika vaccines: can we solve one problem without creating another one?

Abstract

Since 2015, the emergence of epidemic Zika virus transmission have been linked to unparalleled reports of serious neurological disorders and devastating birth defects such as microcephaly and other congenital malformations.1,2 Despite low transmission rates in the past 3 years, the emergence of new Zika outbreaks remains a looming threat. Of particular concern to health authorities worldwide is the possibility of multiple flavivirus outbreaks, as Zika became endemic in the same regions as dengue viruses.