Abstract
30Sep 2016 ZEIN NANOPARTICLE AS SAFE EFFECTIVE BIOCOMPATIBLE NANOCARRIER Shaimaa Mohammed Ewais , Rania Hassan Fahmy , Laila Ahmed Rashid and Fathia Zaki El-Sharkawi. Department of Biochemistry and Molecular biology, Faculty of Pharmacy Helwan University. Department of Pharmaceutics and Industrial pharmacy, Faculty of Pharmacy Cairo University. Department of Biochemistry and Molecular biology, Faculty of Medicine Cairo University.
Highlights
This study revealed that Zein nanoparticles (ZNPs) is a safe NPs with excellent biocompatibility and minimal toxicity toward viable cells that confirmed by invitro cytotoxic analysis of HepG2 cell lines using neutral red assay
The application of natural polymers on colloidal systems facilitates the fabrication of nanomaterials with several attractive features such as high biocompatibility, biodegradability and low toxicity
The surface of zein molecules includes more than 50% hydrophobic amino acid residues and is typically dissolved in 70–80% aqueous ethanol before dispersion into water to precipitate zein as NPs, which can simultaneously encapsulate various lipophilic compounds co-dissolved in aqueous
Summary
Zein nanoparticles (ZNPs) is protein nanoparticles (NPs) that can Received: 12 July 2016 Final Accepted: 19 August 2016 Published: September 2016 effectively carry wide range of both hydrophobic and hydrophilic drugs. This study revealed that ZNP is a safe NPs with excellent biocompatibility and minimal toxicity toward viable cells that confirmed by invitro cytotoxic analysis of HepG2 cell lines using neutral red assay.
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
