Abstract
Abstract Aflatoxin B1 is acutely toxic to embryos and larvae of zebra fish, Brachydanio rerio (Hamilton-Buchanan). These organisms are sensitive to sub-microgram quantities of the toxin and can be used as bioassay test organisms. The larval response is easier to measure than embryonic response, and a standard dosage-mortality curve for the larvae can be developed in 33 hr. As an aflatoxin bioassay test organism, the larvae of zebra fish have several advantages over other test organisms, including ducklings, embryos, and tissue cultures. They require no special skill or equipment and can be obtained easily in the laboratory throughout the year.
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