Abstract
The Z-selective intramolecular Horner–Wadsworth–Emmons reaction of the substrates 7– 12 (RO) 2P(O)CHR′CO 2Et (R′ = (CH 2) n CHO) (R = Ph or o- tBuC 6H 4) gives the 13–18-membered cyclic alkenes selectively (up to Z: E = 97:3) in good yields using NaH in THF under high dilution conditions.
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