Abstract
In the title compound, C25H24N2O3S, the dihedral angles between the thiazole ring and the phenyl and substituted benzene rings are 84.91 (11) and 11.58 (10)°, respectively. The dihydropyrimidine ring adopts a flattened boat conformation. The olefinic double bond is in a Z configuration.
Highlights
C25H24N2O3S, the dihedral angles between the thiazole ring and the phenyl and substituted benzene rings are 84.91 (11) and 11.58 (10), respectively
The olefinic double bond is in a Z configuration
Supplementary data and figures for this paper are available from the IUCr electronic archives (Reference: RN2098)
Summary
Key indicators: single-crystal X-ray study; T = 293 K; mean (C–C) = 0.003 A; R factor = 0.050; wR factor = 0.155; data-to-parameter ratio = 15.0. C25H24N2O3S, the dihedral angles between the thiazole ring and the phenyl and substituted benzene rings are 84.91 (11) and 11.58 (10), respectively. The dihydropyrimidine ring adopts a flattened boat conformation. The olefinic double bond is in a Z configuration. Related literature For related structures, see: Kulakov et al (2009); Zhao et al (2011). For background to the biological properties of fused pyrimidine derivatives, see: Al-Rashood & Abdel-Aziz (2010); Ashok et al (2007); Jang et al (2011); Wichmann et al (1999)
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