Young‐Tae Chang

Abstract

Angewandte Chemie International EditionVolume 55, Issue 36 p. 10554-10554 Author ProfileFree Access Young-Tae Chang First published: 06 April 2016 https://doi.org/10.1002/anie.201602703AboutSectionsPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Graphical Abstract “My favorite author (fiction) is Shiono Nanami. My favorite pieces of music are The Phantom of the Opera and Mozart's Requiem. ...” This and more about Young-Tae Chang can be found on page 10554. 1 Table 1. Young-Tae Chang Date of birth: August 17, 1968 Position: Professor, Department of Chemistry, National University of Singapore (NUS) E-mail: chmcyt@nus.edu.sg Homepage: http://ytchang.science.nus.edu.sg/ ORCID: 0000-0002-1927-3688 Education: 1991 BS, POSTECH 1997 PhD with Sung-Kee Chung, POSTECH 1997–2000 Postdoc with Peter G. Schultz, University of California, Berkeley, and The Scripps Research Institute Awards: 2005 NSF Career Award; 2012 Outstanding Scientist Award, Faculty of Science, NUS Current research interests: Universal platforms for bioimaging and sensing; artificial tongues; molecular evolution; molecular cellomics Hobbies: Korean drumming, photography, forensic science, history, Evernote My favorite author (fiction) is Shiono Nanami. My favorite pieces of music are The Phantom of the Opera and Mozart's Requiem. The most important thing I learned from my parents is be welcoming to the guests who come to my home. If I could have dinner with three famous scientists from history, they would be Albert Einstein, R. B. Woodward, and Archimedes. My not-so-secret passion is to make the invisible become visible. If I were not a scientist, I would be an oriental medical doctor working with acupuncture and natural products. My greatest achievement has been establishing the diversity-oriented fluorescence library approach (DOFLA) for universal probe and sensor development. My worst nightmare is going back to army camp. My biggest motivation is to help solve problems for anybody who seeks a solution. The best advice I have ever been given is “try to be excellent, not to be perfect”. My most exciting discovery to date has been creating a colorful fluorescent chemical library. The most significant scientific advance of the last 100 years has been the development of quantum mechanics. My 5 top papers: References 1“Synthesis and application of functionally diverse 2,6,9-trisubstituted purine libraries as CDK inhibitors”: Y.-T. Chang, N. Gray, G. R. Rosania, D. P. Sutherlin, S. Kwon, T. Norman, R. Sarohia, M. Leost, L. Meijer, P. G. Schultz, Chem. Biol. 1999, 6, 361. (Led to many follow-up works.) 2“Forward chemical genetic approach identifies new role for GAPDH in insulin signalling”: J.-K. Min, Y. K. Kim, P. G. Cipriani, M. Kang, S. M. Khersonsky, D. P. Walsh, J.-Y. Lee, S. Niessen, J. R. Yates, K. Gunsalus, F. Piano, Y.-T. Chang, Nat. Chem. Biol. 2007, 3, 55. (Tagged library for chemical genetics in order to elucidate a drug candidate for diabetic treatment by using C. elegans screening.) 3“A Fluorescent Rosamine Compound Selectively Stains Pluripotent Stem Cells”: C.-N. Im et al., Angew. Chem. Int. Ed. 2010, 49, 7497; Angew. Chem. 2010, 122, 7659. (Stem cells can selectively be detected and isolated for culture.) 4“Chemical Fluorescent Probe for Detection of Aβ Oligomers”: C. L. Teoh et al., J. Am. Chem. Soc. 2015, 137, 13503. (Not only plaques but also Aβ oligomers can be selectively stained.) 5“NeuO: a Fluorescent Chemical Probe for Live Neuron Labeling”: J. C. Er et al., Angew. Chem. Int. Ed. 2015, 54, 2442; Angew. Chem. 2015, 127, 2472. (Live neurons can be brightly imaged in the whole body of a mouse.) Volume55, Issue36August 26, 2016Pages 10554-10554 ReferencesRelatedInformation