Abstract

Approximately one-third of breast cancer survivors experiences persistent fatigue for months or years after successful treatment completion. There is a lack of evidence-based treatments for cancer-related fatigue, particularly among cancer survivors. This single-arm pilot study evaluated the feasibility and preliminary efficacy of a yoga intervention for fatigued breast cancer survivors based on the Iyengar tradition. Iyengar yoga prescribes specific poses for individuals with specific medical problems and conditions; this trial emphasized postures believed to be effective for reducing fatigue among breast cancer survivors, including inversions and backbends performed with the support of props. Twelve women were enrolled in the trial, and 11 completed the full 12-week course of treatment. There was a significant improvement in fatigue scores from pre- to post-intervention that was maintained at the 3-month post-intervention followup. Significant improvements were also observed in measures of physical function, depressed mood, and quality of life. These results support the acceptability of this intervention and suggest that it may have beneficial effects on persistent post-treatment fatigue. However, results require replication in a larger randomized controlled trial.

Highlights

  • Breast cancer is the most common cancer diagnosed in females, with over 252,150 new cases expected in the United States in 2008 [1]

  • There is a lack of evidence-based treatments for cancer-related fatigue, among cancer survivors. This single-arm pilot study evaluated the feasibility and preliminary efficacy of a yoga intervention for fatigued breast cancer survivors based on the Iyengar tradition

  • Iyengar yoga prescribes specific poses for individuals with specific medical problems and conditions; this trial emphasized postures believed to be effective for reducing fatigue among breast cancer survivors, including inversions and backbends performed with the support of props

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Summary

Introduction

Breast cancer is the most common cancer diagnosed in females, with over 252,150 new cases expected in the United States in 2008 [1]. With advances in detection and treatment, the number of women who survive breast cancer has increased significantly in recent years. As survival times increase, addressing the impact of breast cancer and its treatment on long-term outcomes have become increasingly important [2]. Better understanding and management of cancer-related symptoms is critical for reducing suffering in cancer survivors, as highlighted by a recent State of the Science conference sponsored by the National Institutes of Health [3]. Fatigue is the most common and disabling symptom among women successfully treated for breast cancer [4, 5]

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