Abstract
Neurodevelopment The sensory hair cells housed in the inner ear develop sequentially in organized rows. The progenitor cells exit the cell cycle in order and then differentiate in the opposite order. Prajapati-DiNubila et al. show that the cytokine activin A and its antagonist follistatin regulate expression of the transcription factor ATOH1 and thus of hair cell differentiation. Activin A activated expression of ATOH1, whereas follistatin reduced its expression. Similarly, follistatin signaling regulated the number of inner hair cells. eLife 10.7554/eLife.47613 (2019).
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
