Abstract

Several biological parameters have been measured in populations of budding yeast growing in a glucose-limited chemostat, both in steady state and during perturbed growth conditions. The population structure has been determined with a segregated data analysis performed on protein distribution and on volume distributions. A new structured model for budding yeast population is presented, in which the entire system is described only in terms of critical cell mass parameters. This approach allows to integrate in a fairly simple way the population model with the bioreactor performance and to describe transient states of growth.

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