Abstract

We summarize original research in the field of critical care nephrology accepted or published in 2012 in Critical Care and, when considered relevant or directly linked to this research, in other journals. Three main topics have been identified for a rapid overview: acute kidney injury, detailed in some pathogenetic and epidemiological aspects; fluid overload as a predictor of mortality both in acute kidney injury and renal replacement therapy (RRT) patients; and RRT, evaluating some features of citrate anticoagulation and describing the effects of RRT modalities or timing on survival.

Highlights

  • Intrarenal hemodynamics Acute kidney injury (AKI) pathogenesis is currently widely debated and intense scientific efforts are being made to better elucidate mechanisms of renal damage

  • Bragadottir and coauthors were interested in studying intrarenal hemodynamics, and they conducted an interventional study on 11 post-cardiosurgical patients with signs of AKI [5]

  • Burn-associated and contrast-induced acute kidney injury Continuing along the path of AKI pathogenesis, it must be remarked, once again, that critically ill patients undergo different types of AKI and that it is very important to recognize exact AKI etiology in order to optimize its management [6]

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Summary

Introduction

Intrarenal hemodynamics Acute kidney injury (AKI) pathogenesis is currently widely debated and intense scientific efforts are being made to better elucidate mechanisms of renal damage. As suggested by Cely and colleagues, critically ill patients undergoing administration of contrast media should be enrolled in most of these studies to definitely clarify the additional CIN risk in this high risk of AKI population [11].

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