Abstract
XY and ZW: Is Meiotic Sex Chromosome Inactivation the Rule in Evolution?
Highlights
There are two intriguing consequences of having unequal sex chromosomes
The second consequence of unequal sex chromosomes is the absence of a full pairing partner during meiosis in the heterogametic sex [6]
Mammalian MSUC/MSUD results in meiotic sex chromosome inactivation (MSCI), by which the X and Y alone become transcriptionally inactivated during the first meiotic prophase [6,13,14,15]
Summary
There are two intriguing consequences of having unequal sex chromosomes. Dosage compensation involves transcriptional inactivation of one X chromosome in the female. For sex chromosomes, pairing occurs either partially or not at all.
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