Xugu-Huoxue decoction combined with anatomical reduction and internal fixation with cannulated screws for femoral neck fractures

Abstract

Objective To evaluate the clinical effect of Xugu-Huoxue decoction combined with anatomical reduction and internal fixation with cannulated screws in patients with femoral neck fractures. Methods A total of 89 patients with femoral neck fractures were randomly divided into a control group and a Xugu-Huoxue group according to the random number table, with 46 in the control group and 45 in the Xugu-Huoxue group. The control group was treated with anatomical reduction and internal fixation with cannulated screws, while the Xugu-Huoxue decoction group was treated with Xugu-Huoxue decoction on the basis of the control group. The hemodynamics of the femoral vein was evaluated with color Doppler sonography. Hip function was rated with Harris hip score. Results After 12 months of treatment, the minimum diastolic velocity (12.0 ± 2.2 cm/s vs. 9.3 ± 2.0 cm/s; t=3.675, P<0.01), diameter (0.8 ± 0.3 cm vs. 0.6 ± 0.1 cm; t=3.675, P<0.01) and blood flow (1 123.4 ± 271.1 ml/min vs. 901.2 ±121.1 ml/min; t=5.067, P<0.01) of the femoral vein in the Xugu-Huoxue decoction group were significantly increased than those in the control group. The rates of excellent or good in the Xugu-Huoxue decoction group and the control group was 86.7% (39/45) and 63.0% (29/46), respectively, with statistically significant difference (χ2=5.529, P=0.019). There were 2 patients (4.4%) with delayed fracture healing and 2 patients (4.4%) with femoral head necrosis in the Xugu-Huoxue decoction group, while 3 patients (6.5%) with delayed fracture healing, 5 patients (10.9%) with femoral head necrosis in the control group, without statically significant difference (χ2 value were 0.000, 0.572, P value were 1.000, 0.449, respectively). Conclusion Xugu-Huoxue decoction combined with anatomical reduction and internal fixation with cannulated screws can improve the fracture prognosis and the joint function in patients with femoral neck fractures. Key words: Femoral neck fractures; Fracture fixation, internal; Bone screws; Xugu-Huoxue decoction