X-STRs analysis in paternity testing when the alleged father is related to the biological father

Abstract

We report a case where a woman (W) claimed the paternity of a man (M). This man could be her biological father, but he could also be her uncle (i.e. a brother of her actual biological father). Routinely used autosomal markers were first typed yielding one incompatibility among the 17 short tandem repeats (STRs) analyzed. Next a set of 10 X-chromosome STRs (X-STRs) additionally typed allowed to achieve a conclusive result. Thus, the use of this set of X-STRs could be even more informative than the autosomal STRs markers in situations similar to the one presented here.