Abstract

Grating-based x-ray dark-field imaging is a novel imaging modality that has been refined during the past decade for applications in biomedical imaging.1 This technique exploits the wave-like behaviour of x-rays to detect, quantify, and visualise small-angle x-ray scattering. The strength of the dark-field signal reflects the amount of small-angle x-ray scattering that cannot be detected with conventional x-ray devices. Small-angle x-ray scattering occurs at interfaces between structures of different electron density—eg, at air and tissue interfaces in the lung, making the lung an organ of special interest for x-ray dark-field imaging.

Highlights

  • Grating-based x-ray dark-field imaging is a novel imaging modality that has been refined during the past decade for applications in biomedical imaging.[1]

  • The authors report that compared with CT-based parameters, the dark field signal (ρ=0∙62, p

  • Because the dark-field metric showed only a modest correlation with FEV1/FVC ratio in a small cohort of patients, it needs to be validated on a large multiethnic cohort before it can be considered as a screening tool for established disease

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Summary

Introduction

Grating-based x-ray dark-field imaging is a novel imaging modality that has been refined during the past decade for applications in biomedical imaging.[1]. X-ray dark field imaging: a tool for early diagnosis of emphysema in chronic obstructive pulmonary disease?

Results
Conclusion
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