Abstract

Objective To describe the Xinjiang region of tuberculous meningitis (TBM) (age>18 years of age) in patients with the clinical features, analysis of factors influencing the prognosis. Methods A retrospective of cases included in the data collection, describe the clinical characteristics, using the single factor and multiple factors Logistic regression analysis of factors influencing the prognosis. Results A total of 200 cases of TBM patients had the following characteristics: 120 cases of male, female 80 cases; age 18-75 (37.35±14.24)years old; the course of the disease 3-270 (36.86±43.86)days; and 179 cases of survival, 21 cases of death, with a mortality of 10.5%. Single factor analysis showed that hydrocephalus, encephaledema, clinical staging, erythrocyte sedimentation rate, cerebro-spinal fluid (CSF)-protein had statistically significant difference between survival group and death group, respectively (P<0.05). The multi-factor Logistic regression analysis showed that encephaledema and erythrocyte sedimentation rate were independent factors to affect the prognosis of TBM (P<0.05). Conclusions Encephaledema and erythrocyte sedimentation rate are independent risk factors of poor prognosis in patients with TBM, early identify predictors, formulate corresponding clinical countermeasures, and can improve the prognosis of patients with tuberculous meningitis. Key words: Tuberculosis, meningeal/DI/TH/EP; Prognosis

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