Abstract

A manufacturer-funded, open-label randomized trial (SPORTIF III) showed the direct thrombin inhibitor ximelagatran (36 mg twice daily) to be as safe and effective as well-controlled warfarin (target INR, 2.0-3.0) for preventing systemic embolism in patients with nonvalvular atrial fibrillation (NVAF) and at least one additional stroke risk …

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