Abstract

In the Philosophical Transactions for 1845, I showed that not unfrequently in London, the urine was found in many persons to be alkaline from fixed alkali; and I mentioned that Dr. Andrews, at Belfast, had found the water passed at noon of two-thirds of the students of his class to be alkaline. It appeared to me to be a matter of great interest to determine quantitatively the daily variations in the acidity and alkalescence of the urine in the state of health; to trace, if possible, the cause of the variations; to determine the effect of some medicines; at the least until this was done I could draw no conclusions regarding the effect of diseases on the acidity of the urine.

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