Abstract
Fore~qn chemicals in teleost fish are ~rimarilv as the vital antifreezes (Dobbs et al. 19741. Likewise, excreted vla urine and bile. Xenobiotics and their nletabolites the absence of glomeruli may be regarded as a protecexcreted via urine are filtered in the glomerulus and/or tive in B, saida, which survival also secreted by tubular transport within the kidney. Contrary to most fish species, such as the Atlantic cod Gadus ~norhua, the On in 'ystemic (Osuga polar cod Boreogadus saida displays a complete absence of Feeney 1978). the glomerular apparatus. We examined the excretory ro'utes Laminaran is a water-soluble polysaccharide (mol. . in an aglomerular (B. saida) vs a glomerular (G. morhua) wt. -4 .5 kDa) that is readily excreted into the urine in gadoid fish. Using a n inert polysacharride as a model compound, it is demonstrated that this xenobiotic is excreted both mammals and fish. Tritiated laminaran was solelv via the urine in G, morhua and via the bile in B. saida. administered into the caudal vein of both Gadus
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