Abstract

X-Chem has secured drug discovery pacts with two Japanese firms. In what X-Chem calls a transformative deal, Astellas Pharma will use X-Chem’s DNA-encoded libraries to find lead compounds against tough drug targets. X-Chem scores $16 million upfront, as well as research support and milestone payments throughout the multiyear deal. Separately, Ono Pharmaceutical has teamed with X-Chem to develop drug leads against oncology targets.

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