Abstract
Fox-Fordyce disease is a rare, pruritic disorder characterized by multiple flesh-colored follicular papules, usually affecting the apocrine gland-bearing areas of bung women. The typical histopathologic features include a keratotic plug in the dilated follicular orifice and spongiosis of the infundibular epithelium. However, recently, another histopathologic observation has been reported, that of numerous foamy histiocytes in the peri-infundibular dermis. Patients with this xanthomatous form of the disease, have yellow as well as flesh-colored papules. We report a 27-year-old woman with mildly itchy follicular papules in both axillae, mammary areolae and the pubes for one year. Histology revealed numerous xanthomatous cells in association with a few lymphocytes surrounding the follicular infundibulum, consistent with a diagnosis of xanthomatous Fox-Fordyce disease.
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