Abstract
Three patients with different types of xanthomata and hyperlipoproteinaemia are described. One patient had eruptive xanthomata with a Fredrickson Type V hyperlipaemia, the second had tuberose xanthomata and Type III hyperlipaemia, while the third had eruptive, tuberose and tendon sheath xanthomata as well as flat xanthomata of palms without continuous evidence of hyperlipaemia and with impaired glucose tolerance. This patient had shown at times features of Fredrickson Type III hyperlipaemia. The different types of cutaneous xanthomata did not correlate with specific hyperlipaemias. Patients with hyperlipaemia and xanthomatosis appear to be more prone to develop occlusive vascular disease than those without skin lesions. Treatment with diet and serum lipid lowering drugs (nicotinic acid derivatives, Clofibrate, Cholestyramine and thyroid preparations) is discussed.
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