Abstract

Xanthomas have never been produced experimentally, whereas xanthosis has been reproduced. According to Weidman, xanthosis is a term designating those changes, whether local or part of a general hypercholesterolemia, in which tissues become yellow, swollen and characterized histologically by the presence of the so-called xanthoma cells which are not considered pathognomonic for xanthoma. He maintains, however, that when such additional features as distribution, extent and configuration are included, the case becomes a special form of xanthoma. Briefly, xanthosis refers to the basic pathologic process, whereas xanthoma is the term used for the clinical entity. CASE REPORT I. C., a white girl, aged 3 years, was admitted to the dermatologic division after having been seen in consultation with the pediatricians in the isolation ward of Lincoln Hospital, where the tentative diagnoses of conjunctivitis (probably gonorrheal) and eczema had been made on Sept. 22, 1927. It was stated in the history that

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