Xanthogranulomatous Salpingo-Oophoritis Masquerading as an Ovarian Neoplasm: A Case Report

Abstract

Xanthogranulomatous inflammation (XGI) of female genital tract is a chronic inflammatory disease, aetiology and pathogenicity of which are yet unclear. XGI has been reported in multiple organs, most common in kidney and gall bladder (Gray and Libbey in Arch Pathol Lab Med 125:260–263, [1]; Korkes et al. in Urology 71:178–180, [2]. https://doi.org/10.1016/j.urology.2007.09.026 ). Primary XGI involving female genital tract has been reported in only few cases. This study reports a case of xanthogranulomatous salpingo-oophoritis in a 60-year-old postmenopausal woman that gave impression of adnexal mass clinically and radiologically, thereby masquerading as an ovarian malignancy. Histopathological findings revealed characteristic features of XGI. The approach to such a case, differential diagnosis and review of literature are also discussed. The clinical manifestations and diagnostic imaging of XGI of female genital tract can mimic ovarian neoplasm. Although a correct diagnosis is made chiefly through histology, a suggestive preoperative diagnosis can lead to less radical surgery.