Abstract
In this paper we report on the characterization by X-ray computed tomography of calcium phosphate (CaP) and polycaprolactone (PCL) coatings on Ti-6Al-4V alloy scaffolds used as a material for medical implants. The cylindrical scaffold has greater porosity of the inner part than the external part, thus, mimicking trabecular and cortical bone, respectively. The prismatic scaffolds have uniform porosity. Surface of the scaffolds was modified with calcium phosphate (CaP) and polycaprolactone (PCL) by dip-coating to improve biocompatibility and mechanical properties. Computed tomography performed with X-ray and synchrotron radiation revealed the defects of structure and morphology of CaP and PCL coatings showing small platelet-like and spider-web-like structures, respectively.
Highlights
3D scaffolds are biomaterials with predetermined architecture and optimized functionality used as implants for segmental bone reconstruction
In this paper we report on the characterization by X-ray computed tomography of calcium phosphate (CaP) and polycaprolactone (PCL) coatings on Ti-6Al-4V alloy scaffolds used as a material for medical implants
Analysis of the acquitted data reveals that CaP-based layer consists of randomly oriented platelets with CaP particles attached to the scaffold surface and filling the entire space inside one cell of the scaffold structure
Summary
A new application of EBM involves the manufacture of open cellular structures with a predetermined modulus of elasticity or stiffness (E). Typical example of such structures are orthopedic implants designed to prevent bone shielding (stress shielding) by reducing E for high modulus solid metals by more than an order of magnitude [1,2,3]. The idea of multilayered scaffold was in mimicking different type of bone structures including cortical-like (with high density), and trabecular-like (with low density) in one scaffold. The stress-strain curves for all of samples demonstrated considerable ductility which means that parts with different porosities of multilayer scaffolds could change elastic modulus and ultimate compress
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