Abstract

It is customary practice when describing the crystal habit of a given compound to make use of qualitative terms, such as needles or plates. These terms are useful in describing crystal habit as it relates to some important pharmaceutical characteristics, such as suspension stability and syringeability, but inadequate for the more involved processes in which crystal habit affects tableting ability. In this paper a method is presented for describing the crystal habit of a given compound in quantitative terms which may be used, in some instances, to predict tableting behavior and to serve as specifications for tableting materials.

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