Abstract

Diabetes type 1 appears as a single disorder or as an element of autoimmune polyglandular syndrome – APS, mostly concomitant with celiac disease and Hashimoto thyroiditis. AimThe aims of this paper were to evaluate the prevalence of celiac disease and autoimmune thyroid diseases in children and adolescents living in Lower Silesia region and if other condition influenced metabolic control in these patients. Material386 children were included into this study, 199 females (51.5%) and 187 males (48.4%), aged 0.9–18 years, (mean 10.4 y), who were treated between 2006 and 2009. 126 (32.64%) patients used continuous subcutaneous insulin infusion. ResultsIn 37 (9.6%) concomitant autoimmune diseases were diagnosed - celiac disease in 15 (3.9%) patients and thyroid diseases in 22 (5.7%) subjects. HbA1c did not differ in patients with APS vs diabetic subjects (8.3 vs 7.9%, p=0.07). Compensation of thyroiditis and celiac disease was satisfying, proving good compliance. ConclusionsMonitoring of the thyroid function is indicated in patients with diabetes. Screening for celiac disease is an effective method of early diagnosis.

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