WTP2.8 There are Acceptable Allograft Survival outcomes Of Kidney Transplants In recipients From the Black population In The UK, But Are The Outcomes At Par With Caucasians Receiving Renal Transplants?

Abstract

Abstract Purpose Those of black descent make up 22.7% of people in the UK receiving dialysis. A UK Registry data analysis of transplant outcomes on the Black-Population (BP) was done and a comparative assessment with the Caucasian-Population (CP) renal transplant recipients was performed. Methods We harmonized the UK Renal-Transplant Registry Data to shortlist the renal transplants done on Black and Caucasian patients from the year 2000-2019. The demographics and survival analysis at 1,3 and 5 years post-transplant were analyzed. Regression was done to identify survival predictors. Results Renal-Transplant rates in the BP have improved >10 times since the last decade. 18% of transplants in the UK are performed on black-minorities. N=1878 Transplants have been done on the BP since the year 2000 compared to N=28960 on CP cohort. Both Cohorts had similar donor and recipient characteristics with normal distribution. BP was most likely to receive a cadaveric kidney-transplant, while CP had odds of 2.3 times (1.19-4.66) p=0.009 higher to receive a living donor kidney. The eGFR at 3 & 12 months post-transplant was similar in both groups (p=0.77). The median-CIT for cadaveric kidneys was 832 min for BP and 855 min for the CP cohort (p=0.15). The Graft survival was similar in both cohorts at 1,3 and 5 years post-transplant. (CP-87%, 81%, 66%; BP - 87,80%, 64%). Immunologically high-risk (p=0.02), KDRI >1.1(p=0.003), rejection within first 3 months (p=0.01), and CIT>14hrs (p<0.01) predicted poor graft-survival. Conclusions There were no noted differences in renal-transplant outcomes in both black and Caucasian populations. The Transplantation-rates in the BP cohort have impressively increased over the last 10-years.