Abstract

Objectives: After approval of elexacaftor/tezacaftor/ivacaftor (ETI) + ivacaftor (I) in Europe in August 2020, many people with CF (pwCF) experienced a significant improvement in several biomarkers such as pulmonary function test. Here we wanted to evaluate the impact of ETI+I on pulmonary exacerbations over a longer term in German people with CF.

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