Abstract
Lung cancer kills more people in Latin America (LATAM) than any other malignancy, with rising incidence and mortality rates. There are major differences in lung cancer molecular epidemiology across LATAM countries, with recent studies demonstrating how genetic ancestry, with or without ancestry-specific environmental exposure, affects somatic events in lung cancer.1,2 A local Native American ancestry risk score was more strongly correlated with EGFR mutation frequency compared with global ancestry correlation.
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