Abstract
Objectives: Pseudomonas aeruginosa (PA) has a reputation for predatory competition against neighbouring organisms like Staphylococcus aureus (SA) using toxins such as ExoS and cyanide. Despite this, we and others have reported high rates of chronic co-infection. We hypothesize that sustained co-existence occurs with less virulent strains which may limit collateral damage to the host. We explored a large, 20-year dataset to determine the impacts of PA and SA chronic mono- and co-infection on patient FEV1% and number of hospital IV days.
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