Abstract
We investigate the elasticity of an unsupported epithelial monolayer and we discover that unlike a thin solid plate, which wrinkles if geometrically incompatible with the underlying substrate, the epithelium may do so even in the absence of the substrate. From a cell-based model, we derive an exact elasticity theory and discover wrinkling driven by the differential apico-basal surface tension. Our theory is mapped onto that for supported plates by introducing a phantom substrate whose stiffness is finite beyond a critical differential tension. This suggests a new mechanism for an autonomous control of tissues over the length scale of their surface patterns.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have