Abstract

Cerebrospinal fluid and other body fluids from patients with known or suspected malignancy often are submitted to the laboratory It is therefore important to assess these samples carefully for the presence of malignant cells. Although Papanicolaou-stained preparations traditionally have been used for this purpose, Wright-Giemsa-stained cytocentrifuge slides are useful adjuncts in body fluid cytology and may improve the detection of leukemia and lymphoma. However, technologists and pathologists who examine Wright-Giemsa-stained cytocentrifuge slides must be familiar with the appearance of benign variants and malignant cells. This article presents criteria that are useful in making this distinction.

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