Wound infections after median sternotomy treated by VAC therapy, summary of results, and risk factor analysis.

Abstract

The aim of this study is to summarize results and analyze risk factors for the development of wound infection in heart surgery patients after median sternotomy. In this retrospective analysis with assessment of multiple risk factors, we examined 143 patients with infection after median sternotomy treated with VAC therapy from total of 4,650 patients operated in our department from 2012 to 2015. Total of 143 patients developed significant SSI treated by VAC therapy following cardiac surgery. Of these, only 14 patients developed DSWI and one patient was diagnosed with suspected osteomyelitis. BMI, female gender, and use of BIMA proved to be statistically significant risk factors in our study (p < 0.001). The acuteness of operations did not have a statistically significant effect. However, it had a significant effect on the severity of infection (p < 0.01). The severity of infection proved to be a significant prognostic factor for patients' outcome (p < 0.01). In our study, BMI, female gender, and use of BIMA (bilateral internal mammary artery) in patients with DM were predictors for the development of SWI. The acuteness of operation did not have a statistically significant effect. However, it had a statistically significant effect on the severity of infection (Tab. 3, Ref. 30).