Wound healing in pyridoxine deficiency

Abstract

Healing of excision and incision wounds was evaluated in pyridoxine deficient rats. There was a significant decrease in the rate of contraction of excised wound and the period taken for the epithelialization. The tensile strength of incised wound was markedly lower in the deficient group. Food restriction also decreased tensile strength of the incised wound and produced slight retardation in rate of excised wound contraction but the effects were of lesser magnitude than in pyridoxine deficiency.