Abstract

Following refractive surgery, corneal wound-healing and inflammatory responses have important impact on the postoperative outcomes. It has been reported that SMILE induced less keratocyte apoptosis and inflammation compared with femtosecond-LASIK in a rabbit study. Similarly, we also found that the inflammatory and wound healing responses after SMILE was minimal and subsided after 1 week postoperatively. The postoperative complications resulting from impaired wound healing or inflammatory response, such as corneal haze or epithelial ingrowth, are reported to be low and were mainly associated with perioperative complications, such as difficult lenticule extraction.

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