Abstract
Elaeis guineensis of the Arecaceae family is widely used in the traditional medicine of societies in West Africa for treating various ailments. To validate the ethnotherapeutic claims of the plant in skin diseases, wound healing activity was studied. The results showed that E. guineensis leaf extract had potent wound healing capacity as evident from the better wound closure (P < 0.05), improved tissue regeneration at the wound site, and supporting histopathological parameters pertaining to wound healing. Matrix metalloproteinases expression correlated well with the results thus confirming efficacy of E. guineensis in the treatment of the wound. E. guineensis accelerated wound healing in rats, thus supporting its traditional use. The result of this study suggested that, used efficiently, oil palm leaf extract is a renewable resource with wound healing properties.
Highlights
Malaysia is the largest producer of oil palm (Elaeis guineensis Jacq.) in the world and producing more than 7 Million tons of crude palm oil
In Malaysia, for example, 9.9 million tons of solid wastes consisting of oil-palm empty bunch, fiber and fruit shell and 10 million tons of palm oil mill effluent (POME) are generated every year
Significant differencce in the woound closurre was obserrved in treaated group ffrom day 4 onwards annd a the ratee of wound closure waas much faster on laterr days whenn compared with contro ol
Summary
Malaysia is the largest producer of oil palm (Elaeis guineensis Jacq.) in the world and producing more than 7 Million tons of crude palm oil. It is reported that Malaysia alone produced about 30 million tons annually of oil-palm biomass, including trunks, fronds, and empty fruit bunches [3]. One of the significant problems in the palm fruit processing is managing the wastes generated during the processes. In Malaysia, for example, 9.9 million tons of solid wastes consisting of oil-palm empty bunch, fiber and fruit shell and 10 million tons of palm oil mill effluent (POME) are generated every year. In Malaysia, a 3.87 million ha area is used for plantation of oil palm and large quantities of cellulosic and non-cellulosic raw material are generated during harvesting [1,4]. The expansion of plantation in this country has generated large amounts of agro waste, creating problems in replanting operations and tremendous environmental concerns. When left on the plantation floor, these waste materials create great environmental problems [5,6]
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