Wound healing acceleration in inflammation phase of post-tooth extraction after aerobic and anaerobic exercise

Abstract

Summary Background Tooth extraction leads a wound healing that is expected to be physiologically healed in a short time. Both aerobic and anaerobic physical exercises are scientifically proven to enhance various biological functions as well as to accelerate the wound healing in oral mucosa. Aerobic exercise increases tissue oxygenation, accelerates the wound healing and this is different to anaerobic exercise which is considered to produce more free radicals and interferes the wound healing process. Purpose To observe the differences of wound healing effectiveness in the inflammatory phase after tooth extraction based on the number of PMN and macrophage cells in Wistar rats (Rattus norvegicus) that received aerobic and anaerobic exercise. Methods Forty-two rats were divided into three groups: control group (K), aerobic exercise group (P1), and anaerobic exercise group (P2). In each group the number of PMN cells was calculated one day after tooth extraction and the counting of the macrophage cells were performed on the other groups two days later. Data was analyzed statistically using Kruskal Wallis, Levene's test, and proceed with Oneway Anova. Results The highest number of PMN and macrophage cells was obtained in P1 group and the lowest results were in K group. The data between groups demonstrated significant differences. Conclusion This study represents significant differences in the number of PMN and macrophage cells between aerobic and anaerobic exercises in wound healing after tooth extraction which can be a strong indicator of wound healing acceleration in the inflammatory phase.