Abstract
WormBase (https://wormbase.org/) is a mature Model Organism Information Resource supporting researchers using the nematode Caenorhabditis elegans as a model system for studies across a broad range of basic biological processes. Toward this mission, WormBase efforts are arranged in three primary facets: curation, user interface and architecture. In this update, we describe progress in each of these three areas. In particular, we discuss the status of literature curation and recently added data, detail new features of the web interface and options for users wishing to conduct data mining workflows, and discuss our efforts to build a robust and scalable architecture by leveraging commercial cloud offerings. We conclude with a description of WormBase's role as a founding member of the nascent Alliance of Genome Resources.
Highlights
WormBase provides researchers using Caenorhabditis elegans as a model system a carefully curated and highly integrated view of decades of experimental data [1,2]
We describe our progress on curating the primary scientific literature; introduce new interfaces for querying and visualizing sequence and phenotype ontologies; and discuss improvements to the genome browser
We provide a large variety of precomputed data files in a variety of useful formats on our FTP site
Summary
WormBase (https://wormbase.org/) provides researchers using Caenorhabditis elegans as a model system a carefully curated and highly integrated view of decades of experimental data [1,2]. We describe our progress on curating the primary scientific literature; introduce new interfaces for querying and visualizing sequence and phenotype ontologies; and discuss improvements to the genome browser. Additional data types routinely curated for inclusion in WormBase but not currently flagged by our pipeline can still be reported by authors.
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