Abstract

WormBase (http://www.wormbase.org) is an important knowledge resource for biomedical researchers worldwide. To accommodate the ever increasing amount and complexity of research data, WormBase continues to advance its practices on data acquisition, curation and retrieval to most effectively deliver comprehensive knowledge about Caenorhabditis elegans, and genomic information about other nematodes and parasitic flatworms. Recent notable enhancements include user-directed submission of data, such as micropublication; genomic data curation and presentation, including additional genomes and JBrowse, respectively; new query tools, such as SimpleMine, Gene Enrichment Analysis; new data displays, such as the Person Lineage browser and the Summary of Ontology-based Annotations. Anticipating more rapid data growth ahead, WormBase continues the process of migrating to a cutting-edge database technology to achieve better stability, scalability, reproducibility and a faster response time. To better serve the broader research community, WormBase, with five other Model Organism Databases and The Gene Ontology project, have begun to collaborate formally as the Alliance of Genome Resources.

Highlights

  • WormBase is a critically important public information resource for nematode research

  • The first two areas are centered around the nematode species Caenorhabditis elegans and other experimentally tractable nematodes such as Caenorhabditis briggsae

  • Information in this area is primarily accessible through the main web portal http://www. wormbase.org

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Summary

INTRODUCTION

WormBase is a critically important public information resource for nematode research. The first two areas are centered around the nematode species Caenorhabditis elegans and other experimentally tractable nematodes such as Caenorhabditis briggsae Information in this area is primarily accessible through the main web portal http://www. We joined the Alliance of Genome Resources (AGR) to provide a uniform portal of knowledge for major model organisms for medical research. Our goal is to facilitate research by providing up-to-date, high quality and curated information that is useful, easy to find and, easy to comprehend To this end, we constantly make improvements to data acquisition, processing and presentation.

Community curation of research literature
DATA QUERY TOOLS
Gene set enrichment analysis
WEBSITE AND INFRASTRUCTURE
Genome browsing
SObA phenotype graph
Person intellectual lineage browser
WormBase ParaSite
Findings
THE ALLIANCE OF GENOME RESOURCES
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