Abstract
The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RSCB PDB) provides a wide range of digital data regarding biology and biomedicine. This huge internet resource involves a wide range of important biological data, obtained from experiments around the globe by different scientists. The Worldwide Protein Data Bank (wwPDB) represents a brilliant collection of 3D structure data associated with important and vital biomolecules including nucleic acids (RNAs and DNAs) and proteins. Moreover, this database accumulates knowledge regarding function and evolution of biomacromolecules which supports different disciplines such as biotechnology. 3D structure, functional characteristics and phylogenetic properties of biomacromolecules give a deep understanding of the biomolecules’ characteristics. An important advantage of the wwPDB database is the data updating time, which is done every week. This updating process helps users to have the newest data and information for their projects. The data and information in wwPDB can be a great support to have an accurate imagination and illustrations of the biomacromolecules in biotechnology. As demonstrated by the SARS-CoV-2 pandemic, rapidly reliable and accessible biological data for microbiology, immunology, vaccinology, and drug development are critical to address many healthcare-related challenges that are facing humanity. The aim of this paper is to introduce the readers to wwPDB, and to highlight the importance of this database in biotechnology, with the expectation that the number of scientists interested in the utilization of Protein Data Bank’s resources will increase substantially in the coming years.
Highlights
IntroductionThe Protein Data Bank (PDB) is known as an international virtual data core, which serves as a fundamental information source in association with atomic structures, crystallography and three-dimensional (3D) structures of biomolecules, including nucleic acids and proteins (e.g., enzymes, immunoglycoproteins, adhesins) which are applicable for education and research
The aim of this paper is to introduce the readers to Worldwide Protein Data Bank (wwPDB), and to highlight the importance of this database in biotechnology, with the expectation that the number of scientists interested in the utilization of Protein Data Bank’s resources will increase substantially in the coming years
The Protein Data Bank (PDB) is known as an international virtual data core, which serves as a fundamental information source in association with atomic structures, crystallography and three-dimensional (3D) structures of biomolecules, including nucleic acids and proteins which are applicable for education and research
Summary
The Protein Data Bank (PDB) is known as an international virtual data core, which serves as a fundamental information source in association with atomic structures, crystallography and three-dimensional (3D) structures of biomolecules, including nucleic acids and proteins (e.g., enzymes, immunoglycoproteins, adhesins) which are applicable for education and research. Since 1971, the PDB as the first global open access recourse, which serves invaluable digital data for free This international public good, supports vital data and information to visualize the biological structures and the related bindings between macro- and small biomolecules. Since 2013, the management of PDB is in accordance with the FAIR (the acronym depicts: Findable, Accessible, Interoperable, Reusable)
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