Abstract
Skin and soft tissue infections (SSTIs) encompass a variety of pathological conditions ranging from simple superficial infections to severe necrotizing soft tissue infections. Necrotizing soft tissue infections (NSTIs) are potentially life-threatening infections of any layer of the soft tissue compartment associated with widespread necrosis and systemic toxicity. Successful management of NSTIs involves prompt recognition, timely surgical debridement or drainage, resuscitation and appropriate antibiotic therapy. A worldwide international panel of experts developed evidence-based guidelines for management of soft tissue infections. The multifaceted nature of these infections has led to a collaboration among surgeons, intensive care and infectious diseases specialists, who have shared these guidelines, implementing clinical practice recommendations.
Highlights
Skin and soft tissue infections (SSTIs) encompass a variety of pathological conditions ranging from simple superficial infections to severe necrotizing soft tissue infections
SSTIs may affect any part of the body, the lower extremities, the perineum, and the abdominal wall are the most common sites of involvement
Necrotizing soft tissue infections (NSTIs) appears to have decreased over the past decade, possibly due to improved recognition and earlier delivery of more effective therapy [2]
Summary
2. Ustin JS, Malangoni MA: Necrotizing soft-tissue infections. 5. Merlino JI, Malangoni MA: Complicated skin and soft-tissue infections: diagnostic approach and empiric treatment options. 6. Napolitano LM: Severe soft tissue infections. 7. Stevens DL, Bisno AL, Chambers HF, Everett ED, Dellinger P, Goldstein EJ, Gorbach SL, Hirschmann JV, Kaplan EL, Montoya JG, Infectious Diseases Society of America, Wade JC: Practice guidelines for the diagnosis and management of skin and soft-tissue infections. 8. Eron LJ, Lipsky BA, Low DE, Nathwani D, Tice AD, Volturo GA: Expert panel on managing skin and soft tissue infections. Managing skin and soft tissue infections: expert panel recommendations on key decision points. Treatment of complicated skin and soft tissue infections.
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