Abstract

SummaryQ. 1 Chemokines are produced by lung cells after exposure to proinflammatory cytokines or mast cell productsQ. 2 Characterization of the CD23 sheddase: A potential target for treating allergyQ. 3 Application of live and heat killed BCG but not purified protein derivative from Mycobacterium tuberculosis inhibits allergen-induced airway eosinophiliaQ. 4 IL-4 and IL-4Rα knockout mice produce specific IgE leading to anaphylaxis upon prolonged allergen exposureQ. 5 Expression and function of histamine receptors 1 and 2 on human monocyte-derived dendritic cellsQ. 6 Inhibition of the IL-4/IL-13 receptor system in a mouse model for allergic asthmaQ. 7 Novel genetic variation of the human interleukin-21 receptor suggests involvement in IgE synthesisQ. 8 Local immune reactions in vitro: Skin models for the discrimination between irritation and sensitizationQ. 9 Characterization of the T cell reactivity to Art v 1, the major mugwort pollen allergen, reveals a single immunodominant epitopeQ. 10 Modulation of in vitro cytokine production of PBMCs by the indoor air pollutant styrene using a newly established bioreactor systemQ. 11 Indoor exposure to volatile organic compounds is associated with T cell polarization towards the type 2 phenotype and allergic sensitization to food allergens: Results of the LARS studyQ. 12 T cell receptor modulation in Chi t 1-9 allergic subjects and controlsQ. 13 Are volatile organic compounds involved in the triggering of allergic disorders? A new bioreactor system to measure immunomodulating effects of volatile organic compoundsQ. 14 Sub-toxic doses of irritants and contact allergens induce expression of costimulatory molecules on monocyte-derived dendritic cellsQ. 15 DNA immunization focussed on dendritic cells in a mouse model of type I allergyQ. 16 A new role for albumin in nickel-specific human T cell activationQ. 17 A locus mapped on mouse chromosome 10 controlling IgE production is homologous with a segment on human chromosome 12, containing a locus that determines IgE levels in patients with atopyQ. 18 Genomic organization and single nucleotide polymorphism map of the rat interleukin-4 receptor and its putative promoter regionQ. 19 The mycotoxins gliotoxin, patulin, and penicillic acid favor Th2 cytokine productionQ. 20 Cross-sensitization to haptens can be due to different mechanisms: Formation of common haptenic metabolites, T cell recognition of cryptic peptides, and true cross-reactivity of T cells

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