Abstract

Fantastic Voyage—the film in which a miniaturized Raquel Welch and her colleagues venture a patient's bloodstream in a tiny submarine—no longer seems so fantastical. Recent news reports have described a camera-containing pill that photographs the digestive tract. And Japanese researchers have now made microdevices that could proceed the body through even the smallest blood vessels, for example, to deliver clinical treatments [Nature, M29 697 (2001)]. Applied physics professor Satoshi Kawata and coworkers at Osaka University have crafted what they say are the smallest model animals and among the smallest functional micromechanical systems ever made. Their micro-bulls are 10 pm long and 7 pm high, about the size of a red blood cell. Their similarly sized micro-oscillator system consists of a bead fastened to a spring attached to a cubic anchor. The scientists employ laser-trapping force to catch hold of the bead and pull on it. When released, the ...

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