Abstract
Introduction: Cognitive deficits in bipolar disorders persist after the subsidence of active symptoms. This study was carried out to assess the working memory of patients with bipolar disorder in euthymic state.
 Material And Method: Forty euthymic bipolar patients attending a tertiary care mental hospital with equal number of matched controls in terms of age, sex and education were included in the study. Working memory assessments was done using WAIS-III digit span subtest.
 Results: The mean of total digit span test for case group was 8.48±2.04 similarly it was 10.33±2.32 for the controls. The result showed that the mean digit span of cases and control groups are significantly different (p value of < 0.01). The Pearsons correlation between the clinical variables and working memory test in euthymic bipolar patients (case group) was found that the total score for digit span test was negatively correlated with all other clinical variables However, this correlation was found to be non-significant.
 Conclusion: The working memory impairment persists in remitted bipolar disorder patients and this may represent underlying trait abnormality not the state abnormality.
Highlights
Cognitive deficits in bipolar disorders persist after the subsidence of active symptoms
The Pearsons correlation between the clinical variables and working memory test in euthymic bipolar patients was found that the total score for digit span test was negatively correlated with all other clinical variables this correlation was found to be non-significant
The working memory impairment persists in remitted bipolar disorder patients and this may represent underlying trait abnormality not the state abnormality
Summary
Cognitive deficits in bipolar disorders persist after the subsidence of active symptoms. This study was carried out to assess the working memory of patients with bipolar disorder in euthymic state. It has been found that patients with bipolar disorder in a euthymic state experience difficulties in various domains of social, cognitive and occupational functioning.[5,6] A study by Thompson et al, found that euthymic bipolar clients have a deficit in their ability to monitor the contents of working memory.[7] Another study found that the bipolar patients in remission seems to be both affectively disturbed and have impaired working memory.[8] study have shown subtle deficits were present in attention and working memory during euthymic period of bipolar illness but those deficits weren’t statistically significant.[9]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
