Abstract
Dimethyl 2-isopropoxycarbonyl-1, 2-dihydroisoquinoline-1-phosphonate ( 1 ) was prepared from isoquinoline, isopropyl chloroformate, and trimethyl phosphite. Wittig-Horner reaction of 1 with various aldehydes afforded the corresponding exo-methylene compounds, which were converted to 1-substituted isoquinolines with hydrogen chloride.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
