Abstract
WITHDRAWN: Evaluation of clinical, pathological and genetic indicators in chickens with thiram-induced tibial dyschondroplasia
Highlights
Tibial dyschondroplasia (TD) is an important tibiotarsal bone disease in fast-growing birds that disturbs the proximal tibial growth plate [1]
The results indicated that lameness was increased significantly throughout the experiment in the TD group of chickens compared with the normal group
A higher degree of lameness was recorded on day 7 and 10, and after that, it started to decrease, while the normal group of chickens remained healthy throughout the experimental period without showing any signs of lameness (Figure 2)
Summary
Tibial dyschondroplasia (TD) is an important tibiotarsal bone disease in fast-growing birds that disturbs the proximal tibial growth plate [1]. Previous research has indicated that almost 30% of bone disease in chickens and turkeys is due to TD and that the disease leads to greater than 10% morbidity in China, creating serious economic losses in the poultry industry [4,5,6]. Research focuses on increasing the growth rate and feed conversion ratio (FCR) of broilers; poultry bone disease incidence is increasing in the broiler industry [5, 14, 15]. Normal growth plate development requires cartilage vascularization and mineralization followed by osteogenesis, while in tibial dyschondroplasia, the differentiation of chondrocytes appears to be abnormal [7, 11]
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