Abstract
WITHDRAWN: Association between <i>ADIPOQ</i> rs2241766 polymorphism and risk of diabetic nephropathy
Highlights
In diabetic patients, microvascular lesions and accelerated atherosclerosis tend to trigger complications leading to severe morbidity [1]
The overall Odds ratios (ORs) reflected a positive correlation between ADIPOQ rs2241766 polymorphism and susceptibility to Diabetic nephropathy (DN) under GG vs. TT and GG vs. TT + TG comparisons (OR = 1.51, 95% confidence intervals (95% CIs) = 1.16–1.95; OR = 1.43, 95% CI = 1.11–1.85)
ADIPOQ rs2241766 polymorphism may be associated with an increased risk of DN, especially in Caucasian and African populations as well as in type 2 diabetes mellitus (T2DM) patients
Summary
Microvascular lesions and accelerated atherosclerosis tend to trigger complications leading to severe morbidity [1]. The ethnic disparity in DN development may be attributed to an important role of genetic factors; and gender has been demonstrated to influence the predisposition of diabetic patients to developing kidney diseases, with males having a relatively higher incidence rate [8,9,10,11]. This meta-analysis was performed to derive a more comprehensive estimation over the role of the single nucleotide polymorphism (SNP) rs2241766 in ADIPOQ gene in the occurrence of DN
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
