Abstract
Abstract Diabetes mellitus is a metabolic disorder disease due to insulin deficiency and glucose monitoring technology has been used for diabetes control. We have been trying to find a low profile, easy fabrication, low cost sensor system for non-invasive monitoring blood glucose. In this paper, we constructed a microwave-based non-invasive monitoring system consisting of a microstrip patch antenna and a TSA spectrum analyzer. In the frequency range of 0.8-3.8 GHz, the non-invasive detection system can effectively detect the concentration of glucose. The minimum detectible glucose concentration was about 0.1 mg/dL (0.0056 mmol/L). Both the result of human blood glucose concentration measured by non-invasive monitoring system and the human blood glucose level measured by fingertip blood sampling were fitted, and the goodness of fit (R 2 ) was 0.93. The results clearly verified the sensitivity and usefulness of the microwave sensing system for non-invasive glucose monitoring. This proposed system provides a unique approach for real contactless glucose monitoring and it may serve as a bloodless glucometer for the calibration of different glucose levels.
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