Abstract
Sodium or calcium polystyrene sulfonate is a cation-exchange resin commonly administered to treat hyperkalaemia. Its side effects include aspiration pneumonitis and digestive complications, such as nausea, vomiting and constipation. Whereas colonic necrosis and perforation are rare complications associated with the medication. Here we describe a case of calcium polystyrene sulfonate-induced colonic necrosis and perforation to remind clinicians of these rare, but potentially lethal, complications associated with this commonly used medication.
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